胡孝林,张亮亮,罗阳

• 1:重庆大学生物工程学院
• 2:重庆大学医学院智慧检验与分子医学中心

摘要(Abstract)：

新型冠状病毒肺炎(Corona Virus Disease 2019,COVID-19)的早期快速实验室检测对病毒感染的治疗与预后监测极其关键,是提高救治效果的最重要手段。传统的基于聚合酶链式反应的核酸检测技术和基于免疫反应的蛋白检测技术是目前早期快速检测的主要手段,但是因方法学本身的限制,每种技术均存在着各自的优缺点。非特异性实验室指标也在COVID-19患者的临床诊疗中具有重要价值。本文主要从核酸、蛋白、常规实验室检测指标三个层面着手,对目前新型冠状病毒的检测方法和策略进行详细论述和对比分析,提出通过综合核酸、蛋白和血清学指标的多指标联合检测有望成为未来感染性疾病临床诊断的重要手段。

关键词(KeyWords)： 新型冠状病毒;实验室检测;聚合酶链式反应;核酸检测;免疫检测

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金项目(81871733);; 重庆市社会民生重点项目(CSTC2016SHMS-ZTZX10005);; 重庆大学“新型冠状病毒肺炎”应急科研专项(2020CDJYGRH-YJ05);; 中央高校基本科研业务费(2019CDYGZD005、 2019CDYGZD007)

作者(Author): 胡孝林,张亮亮,罗阳

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