刘立新;童绥菊;袁海涛;万敏;付薇;

• 1:武汉市东西湖区人民医院急诊科
• 2:武汉市东西湖区人民医院药剂科
• 3:武汉市东西湖区人民医院重症医学科

摘要(Abstract)：

目的 探讨急性心肌梗死(AMI)合并肺部感染患者痰标本病原学特点及心肌酶谱与炎症因子水平变化。方法 选取2021年1-3月武汉市东西湖区人民医院收治的130例AMI患者为病例组，其中合并肺部感染26例(感染组)和未合并感染104例(未感染组),另选取56名健康体检者为对照组。分析肺部感染痰标本分离病原菌分布特点，检测心肌酶谱[谷草转氨酶(AST)、乳酸脱氢酶(LDH)、高敏肌钙蛋白(hsTnl)、肌酸激酶同工酶(CK-MB)]及炎性因子[降钙素原(PCT)、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)指标水平，采用受试者工作特征(ROC)曲线分析炎性因子水平诊断急性心肌梗死患者合并肺部感染的价值。结果 26例AMI合并肺部感染患者痰培养分离出病原菌26株，其中革兰阳性菌及革兰阴性菌占比分别为42.31%、57.69%;病例组炎性因子及心肌酶谱水平均高于对照组(P<0.05),感染组炎性因子水平均高于未感染组(P<0.05)。ROC曲线分析结果显示，PCT、IL-6、TNF-α联合检测诊断急性心肌梗死合并肺部感染的曲线下面积为0.900。结论 AMI合并肺部感染患者分离病原菌以革兰阴性菌为主，炎症因子及心肌酶谱指标均呈高表达，且PCT、IL-6、TNF-α联合检测对AMI合并肺部感染具有较高的诊断价值。

关键词(KeyWords)： 急性心肌梗死;肺部感染;心肌酶谱;炎性因子;诊断价值

Abstract:

Keywords:

基金项目(Foundation): 湖北省卫生健康委员会科研项目(WJ2021F016)

作者(Authors): 刘立新;童绥菊;袁海涛;万敏;付薇;

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