郭永春;曹耀威;王喆;魏驰;汪冰;

• 1:襄阳市中心医院骨四科
• 2:郑州市骨科医院关节外科
• 3:荆州市第一人民医院创伤手足科
• 4:随州市中心医院骨二科

摘要(Abstract)：

目的 分析髋关节置换术后中性粒细胞与淋巴细胞比率(NLR)和D-二聚体(D-D)表达水平及其对术后感染的预测价值。方法 纳入2018年8月-2021年1月襄阳市中心医院行髋关节置换术患者150例，分析其术后感染率和病原菌分布，采用受试者工作特征(ROC)曲线分析NLR、D-D对术后感染的预测价值，多因素分析髋关节置换术后感染的影响因素。结果 16例患者在术后发生感染(10.67%),均为慢性假体周围感染，检出病原菌20株，其中革兰阳性菌、革兰阴性菌分别为12株、8株；感染组术后1 d、3 d、7 d NLR、D-D、血沉、降钙素原(PCT)、C-反应蛋白(CRP)、白细胞计数(WBC)均高于非感染组(P<0.05);术后3 d NLR、D-D预测髋关节置换术后感染的敏感度分别为77.41%、75.18%,特异度分别76.25%、74.59%,曲线下面积分别为0.819、0.810;多因素分析结果，年龄、糖尿病病史、NLR、D-D、手术时间、长期类固醇激素使用史均是髋关节置换术后感染的影响因素(P<0.05)。结论 髋关节置换术后患者可受多因素影响发生感染，而NLR、D-D在髋关节置换术后感染中有一定预测价值，可予以监测。

关键词(KeyWords)： 髋关节置换术;中性粒细胞与淋巴细胞比率;D-二聚体;术后感染;预测价值

Abstract:

Keywords:

基金项目(Foundation): 湖北省科研基金项目(2020HJ021411)

作者(Authors): 郭永春;曹耀威;王喆;魏驰;汪冰;

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